MetaCyc Pathway: methylglyoxal degradation V in Sinorhizobium meliloti 1021

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Reactions and Genes D,L-Lactate (C)
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Methylglyoxal reductase (NADPH-dependent) (in reverse):
methylglyoxal + NADPH + H+→(S)-lactaldehyde + NADP+ (EC 1.1.1.283)
SMc00101 +0.1
Lactaldehyde dehydrogenase:
(S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+ (EC 1.2.1.22)
SM_b20891 -0.3
SMc02322 -0.1
SMc04385 +0.2
L-lactate dehydrogenase (cytochrome):
(S)-lactate + 2 an oxidized c-type cytochrome→pyruvate + 2 a reduced c-type cytochrome + 2 H+ (EC 1.1.2.3)
SM_b20850 -1.2
SM_b20858 -0.1
SMa0404 -0.1
SMc01712 -0.2
SMc01740 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information