MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Burkholderia phytofirmans PsJN

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Reactions and Genes D-Galactose (C)
remove
propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
BPHYT_RS01050 -0.1
BPHYT_RS04770 +0.0
BPHYT_RS05365 -0.2
BPHYT_RS05385 +0.3
BPHYT_RS06420 N.D.
BPHYT_RS07065 -0.0
BPHYT_RS08285 N.D.
BPHYT_RS08365 -0.0
BPHYT_RS08890 -0.2
BPHYT_RS10170 +0.1
BPHYT_RS10200 N.D.
BPHYT_RS10595 -0.1
BPHYT_RS10630 +0.1
BPHYT_RS10735 N.D.
BPHYT_RS11845 N.D.
BPHYT_RS13055 -0.5
BPHYT_RS14425 N.D.
BPHYT_RS15135 +0.1
BPHYT_RS15890 -1.4
BPHYT_RS16040 N.D.
BPHYT_RS16940 -2.2
BPHYT_RS20510 N.D.
BPHYT_RS20625 +0.1
BPHYT_RS20775 +0.5
BPHYT_RS21600 +0.1
BPHYT_RS22135 -0.2
BPHYT_RS25030 -0.1
BPHYT_RS25415 N.D.
BPHYT_RS25655 +0.1
BPHYT_RS26470 +0.6
BPHYT_RS28250 N.D.
BPHYT_RS30440 +0.0
BPHYT_RS30465 -1.2
BPHYT_RS30795 -0.2
BPHYT_RS31385 +0.3
BPHYT_RS31405 N.D.
BPHYT_RS31610 +0.0
BPHYT_RS31900 -0.2
BPHYT_RS33140 N.D.
BPHYT_RS33705 -0.1
BPHYT_RS34945 N.D.
BPHYT_RS34965 N.D.
BPHYT_RS35505 -0.2
BPHYT_RS35675 -0.2
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
BPHYT_RS12085 N.D.
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information