MetaCyc Pathway: Entner-Doudoroff pathway III (semi-phosphorylative) in Burkholderia phytofirmans PsJN

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Reactions and Genes D-Galactose (C)
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Glucose 1-dehydrogenase (NADP(+)):
D-glucopyranose + NADP+→D-glucono-1,5-lactone + NADPH + H+
(EC 1.1.1.119; 1.1.1.360)
BPHYT_RS35785 +0.3
Gluconolactonase:
D-glucono-1,5-lactone + H2O→D-gluconate + H+
(spontaneous) (EC 3.1.1.17)
BPHYT_RS21245 -0.2
BPHYT_RS24170 +0.2
D-gluconate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.140; 4.2.1.39)
BPHYT_RS09885 +0.4
BPHYT_RS16405 -2.6
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
BPHYT_RS09175 +0.0
BPHYT_RS11300 N.D.
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate
(EC 4.1.2.14; 4.1.2.55)
BPHYT_RS16730 N.D.
D-glyceraldehyde 3-phosphate + NAD(P)+ + H2O→3-phospho-D-glycerate + NAD(P)H + 2 H+ (EC 1.2.1.90)
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3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BPHYT_RS02590 -4.3
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O
(EC 4.2.1.11)
BPHYT_RS12675 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP
(EC 2.7.1.40)
BPHYT_RS16265 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information