MetaCyc Pathway: superpathway of methylglyoxal degradation in Sinorhizobium meliloti 1021

Reactions and Genes	L-Arabinose (C)
Methylglyoxal reductase (NADPH-dependent) (in reverse): methylglyoxal + NADPH + H+→(S)-lactaldehyde + NADP+ (EC 1.1.1.283)
SMc00101	-0.2
Lactoylglutathione lyase (in reverse): methylglyoxal + glutathione→(R)-S-lactoylglutathione (EC 4.4.1.5)
SMa0722	-0.1
SMa0723	+0.1
SMc00290	+0.1
Aldehyde reductase (in reverse): methylglyoxal + NADPH + H+→hydroxyacetone + NADP+ (EC 1.1.1.21)
SM_b20493	-0.0
SMa1410	-0.0
SMc01429	-0.1
Hydroxyacylglutathione hydrolase: (R)-S-lactoylglutathione + H2O→(R)-lactate + glutathione + H+ (EC 3.1.2.6)
SM_b20991	-0.0
SM_b20992	+0.4
SMc00708	+0.1
SMc00709	-0.7
SMc01587	+0.2
Lactaldehyde dehydrogenase: (S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+ (EC 1.2.1.22)
SM_b20891	-3.7
SMc02322	-0.2
SMc04385	+0.7
hydroxyacetone + NADH + H+→(S)-propane-1,2-diol + NAD+
SMc02038	-0.0
(S)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.M6)
No genes
(R)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.12)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information