| Reactions and Genes | L-Phenylalanine as (N) |
|---|
| remove |
| arachidonoyl-CoA + malonyl-CoA + H+→(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+→(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA→(2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + NADPH + H+→adrenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
| adrenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA→(2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| No genes |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA (EC 4.2.1.17) |
| HP15_1141 | +0.4 |
| HP15_12 | -0.1 |
| HP15_1232 | -0.3 |
| HP15_1512 | -0.2 |
| HP15_1737 | -0.0 |
| HP15_1740 | +0.3 |
| HP15_2575 | +0.2 |
| HP15_2692 | -3.1 |
| HP15_2717 | +0.1 |
| HP15_3410 | -0.2 |
| HP15_3941 | -0.4 |
| HP15_4082 | +0.2 |
| HP15_4094 | -0.0 |
| HP15_55 | +0.2 |
| HP15_864 | +0.0 |
| HP15_908 | -0.8 |
| HP15_909 | +0.1 |
| (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| HP15_1009 | +0.2 |
| HP15_1233 | +0.1 |
| HP15_1513 | -0.4 |
| HP15_2344 | +0.2 |
| HP15_2423 | -0.1 |
| HP15_2695 | -3.0 |
| HP15_2996 | -1.0 |
| HP15_35 | -0.2 |
| HP15_3943 | -0.1 |
| HP15_49 | +0.1 |
| HP15_5 | +0.3 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information