MetaCyc Pathway: pyruvate fermentation to butanol I in Marinobacter adhaerens HP15

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Reactions and Genes L-Phenylalanine as (N)
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Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
HP15_3392 +0.1
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
HP15_1009 +0.2
HP15_1233 +0.1
HP15_1513 -0.4
HP15_2344 +0.2
HP15_2423 -0.1
HP15_2695 -3.0
HP15_2996 -1.0
HP15_35 -0.2
HP15_3943 -0.1
HP15_49 +0.1
HP15_5 +0.3
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
HP15_1232 -0.3
HP15_1512 -0.2
HP15_3941 -0.4
HP15_48 +0.3
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
HP15_1141 +0.4
HP15_12 -0.1
HP15_1512 -0.2
HP15_1737 -0.0
HP15_1740 +0.3
HP15_2575 +0.2
HP15_2692 -3.1
HP15_3941 -0.4
HP15_4082 +0.2
HP15_4094 -0.0
HP15_55 +0.2
HP15_864 +0.0
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
Alcohol dehydrogenase (NADP(+)) (in reverse):
1-butanal + NADPH + H+→butan-1-ol + NADP+ (EC 1.1.1.2)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information