MetaCyc Pathway: dopamine degradation in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes Glycine betaine (C)(N); with MOPS
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Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.4)
PFLU_RS14975 -0.2
PFLU_RS14985 -0.3
PFLU_RS19865 +0.1
Catechol O-methyltransferase:
dopamine + S-adenosyl-L-methionine→3-methoxytyramine + S-adenosyl-L-homocysteine + H+
(EC 2.1.1.6)
No genes
Aryl sulfotransferase:
dopamine + 3'-phosphoadenylyl-sulfate→dopamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+
(EC 2.8.2.1)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+
(EC 1.2.1.3)
PFLU_RS02715 +0.2
PFLU_RS04240 -0.0
PFLU_RS07400 +0.4
PFLU_RS09895 -0.2
PFLU_RS11535 -0.0
PFLU_RS15055 -0.1
PFLU_RS15075 -0.1
PFLU_RS15110 +0.1
PFLU_RS19825 +0.2
PFLU_RS20100 +0.0
PFLU_RS26745 -2.1
PFLU_RS29420 -0.5
Catechol O-methyltransferase:
(3,4-dihydroxyphenyl)acetate + S-adenosyl-L-methionine→homovanillate + S-adenosyl-L-homocysteine + H+
(EC 2.1.1.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information