MetaCyc Pathway: superpathway of ornithine degradation in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes Glycine betaine (C)(N); with MOPS
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Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)
PFLU_RS04045 -0.2
Putrescine aminotransferase:
putrescine + 2-oxoglutarate→4-aminobutanal + L-glutamate (EC 2.6.1.82)
No genes
Glutamate--putrescine ligase:
putrescine + ATP + L-glutamate→γ-glutamyl-L-putrescine + ADP + H+ + phosphate (EC 6.3.1.11)
No genes
Aminobutyraldehyde dehydrogenase:
4-aminobutanal + NAD+ + H2O→4-aminobutanoate + NADH + 2 H+ (EC 1.2.1.19)
PFLU_RS05980 +0.2
PFLU_RS06005 +0.1
PFLU_RS07400 +0.4
PFLU_RS09895 -0.2
PFLU_RS11535 -0.0
PFLU_RS15055 -0.1
PFLU_RS15075 -0.1
PFLU_RS15110 +0.1
PFLU_RS19825 +0.2
PFLU_RS26745 -2.1
PFLU_RS29420 -0.5
4-aminobutanal→1-pyrroline + H2O (spontaneous)
No genes
γ-glutamyl-L-putrescine + dioxygen + H2O→4-(γ-L-glutamylamino)butanal + ammonium + hydrogen peroxide (EC 1.4.3.M3)
PFLU_RS20485 -0.0
4-(γ-L-glutamylamino)butanal + NAD(P)+ + H2O→4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ (EC 1.2.1.99)
No genes
Gamma-glutamyl-gamma-aminobutyrate hydrolase:
4-(γ-L-glutamylamino)butanoate + H2O→4-aminobutanoate + L-glutamate (EC 3.5.1.94)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information