MetaCyc Pathway: ureide biosynthesis in Burkholderia phytofirmans PsJN

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Reactions and Genes R2A control
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IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
BPHYT_RS10250 -0.2
BPHYT_RS12020 N.D.
BPHYT_RS13715 -0.7
BPHYT_RS24710 N.D.
BPHYT_RS27545 +0.2
BPHYT_RS31260 -0.4
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.1
BPHYT_RS03140 -1.7
BPHYT_RS09100 -0.3
BPHYT_RS26570 +0.5
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
No genes
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.3
BPHYT_RS03870 -0.0
BPHYT_RS10825 N.D.
BPHYT_RS15080 +0.0
BPHYT_RS15085 -0.0
BPHYT_RS20910 +0.1
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.4
BPHYT_RS29715 +0.5
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
BPHYT_RS11550 N.D.
BPHYT_RS11555 +0.8
BPHYT_RS26115 -0.4
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
BPHYT_RS11530 +0.1
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information