MetaCyc Pathway: purine nucleotides degradation II (aerobic) in Burkholderia phytofirmans PsJN

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Reactions and Genes R2A control
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5'-nucleotidase:
AMP + H2O→adenosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.1
BPHYT_RS03140 -1.7
BPHYT_RS09100 -0.3
BPHYT_RS26570 +0.5
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
BPHYT_RS10250 -0.2
BPHYT_RS12020 N.D.
BPHYT_RS13715 -0.7
BPHYT_RS24710 N.D.
BPHYT_RS27545 +0.2
BPHYT_RS31260 -0.4
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.1
BPHYT_RS03140 -1.7
BPHYT_RS09100 -0.3
BPHYT_RS26570 +0.5
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium (EC 3.5.4.4)
BPHYT_RS11820 -0.4
BPHYT_RS15095 -0.4
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate (EC 2.4.2.1; 2.4.2.15)
No genes
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.1
BPHYT_RS03140 -1.7
BPHYT_RS09100 -0.3
BPHYT_RS26570 +0.5
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
BPHYT_RS11520 -0.2
BPHYT_RS15100 -0.2
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
No genes
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
No genes
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.3
BPHYT_RS03870 -0.0
BPHYT_RS10825 N.D.
BPHYT_RS15080 +0.0
BPHYT_RS15085 -0.0
BPHYT_RS20910 +0.1
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.4
BPHYT_RS29715 +0.5
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.3
BPHYT_RS03870 -0.0
BPHYT_RS10825 N.D.
BPHYT_RS15080 +0.0
BPHYT_RS15085 -0.0
BPHYT_RS20910 +0.1
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.4
BPHYT_RS29715 +0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information