MetaCyc Pathway: NAD(P)/NADPH interconversion in Klebsiella michiganensis M5al

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Reactions and Genes RCH2_defined_1percent_glucose with Chloride 600 mM
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+
(EC 2.7.1.23; 2.7.1.M29)
BWI76_RS21555 N.D.
NADP+ + H2O→NAD+ + phosphate (EC 3.1.3.108)
BWI76_RS06160 -0.1
NAD+[in] + 4 H+[out] + a ubiquinol→NADH[in] + 5 H+[in] + a ubiquinone (EC 7.1.1.2)
BWI76_RS11175 N.D.
BWI76_RS20130 +0.6
BWI76_RS20135 +0.5
BWI76_RS20140 +0.4
BWI76_RS20145 +0.3
BWI76_RS20150 -0.1
BWI76_RS20155 -0.2
BWI76_RS20160 -0.3
BWI76_RS20165 -0.3
BWI76_RS20170 -0.1
BWI76_RS20175 N.D.
BWI76_RS20180 +0.2
BWI76_RS20185 N.D.
BWI76_RS20190 -0.2
BWI76_RS26595 +0.4
NAD(P)(+) transhydrogenase (B-specific):
NAD+ + NADPH→NADH + NADP+
(EC 1.6.1.1; 1.6.1.3)
BWI76_RS00870 N.D.
BWI76_RS16200 +2.6
BWI76_RS16205 +2.7
NADH kinase:
NADH + ATP→NADPH + ADP + H+
(EC 2.7.1.86; 2.7.1.M29)
No genes
NADPH + H2O→NADH + phosphate (EC 3.1.3.108)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information