MetaCyc Pathway: 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes p-Coumaric (C) 5 mM
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GTP cyclohydrolase I:
GTP + H2O→7,8-dihydroneopterin 3'-triphosphate + formate + H+
(EC 3.5.4.16)
PFLU_RS21315 -0.4
PFLU_RS25310 -0.5
PFLU_RS29970 +1.4
7,8-dihydroneopterin 3'-triphosphate→6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate (EC 4.1.2.60)
No genes
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase:
6-(hydroxymethyl)-7,8-dihydropterin + ATP→(7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+
(EC 2.7.6.3)
PFLU_RS25745 N.D.
PFLU_RS27505 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information