MetaCyc Pathway: L-lysine degradation X in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes 4-Hydroxybenzoic Acid (C) and Ammonium chloride (N); with MOPS
remove
Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2
(EC 4.1.1.18)
PFLU_RS04045 -0.2
PFLU_RS12930 -0.2
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate
(EC 2.6.1.82)
No genes
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+
(EC 1.2.1.19)
PFLU_RS05980 +0.2
PFLU_RS06005 +0.3
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate
(EC 2.6.1.48)
PFLU_RS00915 -1.7
PFLU_RS19725 +0.2
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+
(EC 1.2.1.20)
PFLU_RS00910 -0.5
PFLU_RS09560 +0.2
PFLU_RS19740 +0.7
PFLU_RS20675 +0.2
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate
(EC 2.8.3.13)
PFLU_RS00570 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information