MetaCyc Pathway: 4-hydroxybenzoate biosynthesis I (eukaryotes) in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes L-Ornithine
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
AO353_01120 -0.4
AO353_01210 -1.5
AO353_01655 +0.1
AO353_02065 -0.1
AO353_02295 +0.2
AO353_05105 +1.4
AO353_09180 +0.2
AO353_09990 +0.2
AO353_15915 +0.0
AO353_17700 +0.3
AO353_18575 -0.0
AO353_19150 +0.1
AO353_20540 -2.9
AO353_20995 -0.1
AO353_22840 -0.2
AO353_22920 +1.8
AO353_23080 -0.1
AO353_24850 +0.1
AO353_26890 +0.0
AO353_28150 +0.6
AO353_29325 -0.6
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + H2O→4-hydroxybenzaldehyde + acetate
No genes
4-hydroxybenzaldehyde dehydrogenase:
4-hydroxybenzaldehyde + NAD+ + H2O→4-hydroxybenzoate + NADH + 2 H+ (EC 1.2.1.64)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information