MetaCyc Pathway: TCA cycle VI (Helicobacter) in Enterobacter sp. TBS_079

Add experiment(s):


Reactions and Genes TSB plate, 1:1 coculture with Enterobacter_ludwigii_PH2
remove
2-oxoglutarate synthase:
2-oxoglutarate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→succinyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.3)
No genes
3-oxoacid CoA-transferase:
succinyl-CoA + acetoacetate→succinate + acetoacetyl-CoA (EC 2.8.3.5)
MPMX20_01911 +0.4
MPMX20_01912 +0.0
Succinate dehydrogenase (ubiquinone) (in reverse):
succinate[in] + a menaquinone→fumarate[in] + a menaquinol (EC 1.3.5.1)
MPMX20_00434 -0.2
MPMX20_00435 -0.8
MPMX20_00436 -2.3
MPMX20_00437 -1.2
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
MPMX20_01958 -3.4
MPMX20_02021 -1.4
MPMX20_02022 -0.7
MPMX20_02966 +0.1
(S)-malate + a menaquinone→oxaloacetate + a menaquinol (EC 1.1.5.4)
MPMX20_03168 +0.0
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
MPMX20_01349 -2.7
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
MPMX20_00812 -1.3
MPMX20_02499 +0.1
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
MPMX20_00812 -1.3
MPMX20_02499 +0.1
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
MPMX20_01820 N.D.

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information