MetaCyc Pathway: β-alanine biosynthesis II in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes 10% P. fluorescens FW300-N1B4 spent media from growth in 20 mM putrescine
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Propionate--CoA ligase:
propanoate + ATP + coenzyme A→propanoyl-CoA + AMP + diphosphate (EC 6.2.1.17)
Pf6N2E2_5149 -0.0
Pf6N2E2_5659 -0.0
propanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→acryloyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.1)
Pf6N2E2_3686 +0.2
acryloyl-CoA + H2O→3-hydroxypropanoyl-CoA (EC 4.2.1.116)
Pf6N2E2_1147 -0.0
3-hydroxyisobutyryl-CoA hydrolase:
3-hydroxypropanoyl-CoA + H2O→3-hydroxypropanoate + coenzyme A + H+ (EC 3.1.2.4)
Pf6N2E2_1149 +0.4
3-hydroxypropionate dehydrogenase:
3-hydroxypropanoate + NAD+→3-oxopropanoate + NADH + H+ (EC 1.1.1.59)
No genes
Beta-alanine--pyruvate transaminase:
3-oxopropanoate + L-alanine→β-alanine + pyruvate (EC 2.6.1.18)
Pf6N2E2_3463 +0.1
Pf6N2E2_4512 -2.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information