MetaCyc Pathway: adipate degradation in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes p-Coumaric (C) and Ammonium chloride (N); with MOPS
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Succinate--CoA ligase (ADP-forming):
adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate (EC 6.2.1.5)
PFLU_RS08970 N.D.
PFLU_RS08975 N.D.
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
PFLU_RS02225 -0.1
PFLU_RS16060 +0.2
PFLU_RS26520 -0.2
PFLU_RS27605 -2.4
PFLU_RS27610 +0.1
PFLU_RS27620 -3.6
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17)
PFLU_RS07105 -0.0
PFLU_RS07650 -4.7
PFLU_RS08485 +0.0
PFLU_RS10835 +0.0
PFLU_RS12025 +0.1
PFLU_RS13550 -0.3
PFLU_RS14775 -0.4
PFLU_RS14785 +0.2
PFLU_RS16080 -3.9
PFLU_RS22820 -0.1
PFLU_RS22840 +0.0
PFLU_RS24260 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+ (EC 1.1.1.35)
PFLU_RS07650 -4.7
PFLU_RS11090 -0.2
PFLU_RS22840 +0.0
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174)
PFLU_RS06735 -4.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information