MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Cobalt chloride 0.6 mM
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2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
Pf6N2E2_5858 N.D.
Pf6N2E2_5859 N.D.
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
Pf6N2E2_5852 N.D.
Pf6N2E2_5853 N.D.
Pf6N2E2_5854 N.D.
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
Pf6N2E2_2536 -0.1
Pf6N2E2_3276 -0.2
Pf6N2E2_5489 N.D.
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
No genes
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
Pf6N2E2_1496 -0.5
Pf6N2E2_2127 -1.5
Pf6N2E2_2446 +0.3
Pf6N2E2_2632 -0.2
Pf6N2E2_3173 -0.1
Pf6N2E2_4288 +0.2
Pf6N2E2_4386 -0.6
Pf6N2E2_462 +0.2
Pf6N2E2_5300 -1.5
Pf6N2E2_5813 -0.6
Pf6N2E2_5890 -0.2
Pf6N2E2_5891 N.D.
Pf6N2E2_5895 -0.1
Pf6N2E2_5989 +2.1
Pf6N2E2_637 +0.3
Pf6N2E2_684 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information