MetaCyc Pathway: tetrahydromonapterin biosynthesis in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Cobalt chloride 0.6 mM
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GTP cyclohydrolase I:
GTP + H2O→7,8-dihydroneopterin 3'-triphosphate + formate + H+ (EC 3.5.4.16)
Pf6N2E2_4262 -0.1
Pf6N2E2_5273 +0.6
Pf6N2E2_5815 N.D.
7,8-dihydroneopterin 3'-triphosphate→7,8-dihydromonapterin triphosphate (EC 5.1.99.7)
Pf6N2E2_5272 +2.8
7,8-dihydromonapterin triphosphate + 3 H2O→7,8-dihydromonapterin + 2 H+ + 3 phosphate
No genes
7,8-dihydromonapterin + NADPH + H+→5,6,7,8-tetrahydromonapterin + NADP+ (EC 1.5.1.50)
Pf6N2E2_5274 +3.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information