MetaCyc Pathway: adenosylcobalamin salvage from cobalamin in Klebsiella michiganensis M5al

Reactions and Genes	Fungal_growth_media_mCAFEs_v1 with Thallium(I) acetate 0.05 mg/mL
2 cob(I)alamin + an [oxidized flavoprotein] + 2 H+→2 cob(II)alamin + a [reduced flavoprotein] (spontaneous)
No genes
cob(II)alamin + a [corrinoid adenosyltransferase]→cob(II)alamin-[corrinoid adenosyltranferase] (EC 2.5.1.154; 2.5.1.17)
BWI76_RS08445	-0.2
BWI76_RS11900	+0.7
BWI76_RS20810	+1.8
BWI76_RS23165	+0.1
2 cob(II)alamin-[corrinoid adenosyltranferase] + a [reduced flavoprotein]→2 cob(I)alamin-[corrinoid adenosyltranferase] + an [oxidized flavoprotein] + 2 H+ (spontaneous) (EC 2.5.1.154; 2.5.1.17)
BWI76_RS08445	-0.2
BWI76_RS11900	+0.7
BWI76_RS20810	+1.8
BWI76_RS23165	+0.1
BWI76_RS23180	+0.2
Cob(I)yrinic acid a,c-diamide adenosyltransferase: cob(I)alamin-[corrinoid adenosyltranferase] + ATP + H+→adenosylcob(III)alamin-[corrinoid adenosyltranferase] + triphosphate (EC 2.5.1.17)
BWI76_RS08445	-0.2
BWI76_RS11900	+0.7
BWI76_RS20810	+1.8
BWI76_RS23165	+0.1
Cob(I)yrinic acid a,c-diamide adenosyltransferase: adenosylcob(III)alamin-[corrinoid adenosyltranferase]→adenosylcobalamin + a [corrinoid adenosyltransferase] (EC 2.5.1.17)
BWI76_RS08445	-0.2
BWI76_RS11900	+0.7
BWI76_RS20810	+1.8
BWI76_RS23165	+0.1

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information