MetaCyc Pathway: 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis I in Klebsiella michiganensis M5al

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Reactions and Genes Fungal_growth_media_mCAFEs_v1 with Zinc 2 mM
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5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + carbon monoxide + 5'-deoxyadenosine + formate + L-methionine + 3 H+ (EC 4.1.99.17)
BWI76_RS01555 -1.7
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
BWI76_RS19375 -1.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information