MetaCyc Pathway: superpathway of phospholipid biosynthesis II (plants) in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes Glucose (C) and Ammonium chloride (N); with MOPS; with chloride
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Choline kinase:
choline + ATP→phosphocholine + ADP + H+ (EC 2.7.1.32)
No genes
Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+→sn-glycerol 3-phosphate + NAD(P)+ (EC 1.1.1.94)
PFLU_RS09055 -1.9
L-serine + H+→ethanolamine + CO2
No genes
Ethanolamine kinase:
ethanolamine + ATP→O-phosphoethanolamine + ADP + H+ (EC 2.7.1.82)
No genes
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.15)
PFLU_RS06200 -0.0
PFLU_RS23065 -0.3
PFLU_RS27515 -1.2
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-CoA→a 2-lysophosphatidate + coenzyme A (EC 2.3.1.15)
PFLU_RS06200 -0.0
PFLU_RS23065 -0.3
PFLU_RS27515 -1.2
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.51)
PFLU_RS00040 +1.9
PFLU_RS06865 -0.8
PFLU_RS09240 +0.4
PFLU_RS22825 -0.4
PFLU_RS30075 -0.1
Phosphoethanolamine N-methyltransferase:
O-phosphoethanolamine + S-adenosyl-L-methionine→N-methylethanolamine phosphate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.103)
No genes
Ethanolamine-phosphate cytidylyltransferase:
O-phosphoethanolamine + CTP + H+→CDP-ethanolamine + diphosphate (EC 2.7.7.14)
No genes
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-CoA→a phosphatidate + coenzyme A (EC 2.3.1.51)
PFLU_RS00040 +1.9
PFLU_RS06865 -0.8
PFLU_RS09240 +0.4
PFLU_RS22825 -0.4
PFLU_RS30075 -0.1
N-methylphosphoethanolamine cytidylyltransferase:
N-methylethanolamine phosphate + CTP + H+→CDP-N-methylethanolamine + diphosphate (EC 2.7.7.57)
No genes
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate (EC 2.7.7.41)
PFLU_RS06300 N.D.
PFLU_RS30080 -0.0
Ethanolaminephosphotransferase:
CDP-ethanolamine + a 1,2-diacyl-sn-glycerol→a phosphatidylethanolamine + CMP + H+ (EC 2.7.8.1)
No genes
Phosphoethanolamine N-methyltransferase:
N-methylethanolamine phosphate + S-adenosyl-L-methionine→N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.103)
No genes
CDP-diacylglycerol--inositol 3-phosphatidyltransferase:
a CDP-diacylglycerol + myo-inositol→a 1-phosphatidyl-1D-myo-inositol + CMP + H+ (EC 2.7.8.11)
No genes
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
PFLU_RS10775 N.D.
PFLU_RS30055 -0.0
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+ (EC 2.7.8.8)
PFLU_RS14215 -0.3
PFLU_RS25635 N.D.
a phosphatidylethanolamine + L-serine→ethanolamine + a phosphatidylserine (EC 2.7.8.29)
No genes
Phosphoethanolamine N-methyltransferase:
N-dimethylethanolamine phosphate + S-adenosyl-L-methionine→phosphocholine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.103)
No genes
CDP-N-methylethanolamine + a 1,2-diacyl-sn-glycerol→a phosphatidyl-N-methylethanolamine + CMP + H+
No genes
N-dimethylethanolamine phosphate + CTP + H+→CDP-N-dimethylethanolamine + diphosphate
No genes
Phosphatidyl-N-methylethanolamine N-methyltransferase:
a phosphatidyl-N-methylethanolamine + S-adenosyl-L-methionine→a phosphatidyl-N-dimethylethanolamine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.71)
No genes
Choline-phosphate cytidylyltransferase:
phosphocholine + CTP + H+→CDP-choline + diphosphate (EC 2.7.7.15)
No genes
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
No genes
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2 (EC 4.1.1.65)
PFLU_RS02495 N.D.
CDP-N-dimethylethanolamine + a 1,2-diacyl-sn-glycerol→a phosphatidyl-N-dimethylethanolamine + CMP + H+
No genes
Diacylglycerol cholinephosphotransferase:
CDP-choline + a 1,2-diacyl-sn-glycerol→a phosphatidylcholine + CMP + H+ (EC 2.7.8.2)
No genes
Phosphatidyl-N-methylethanolamine N-methyltransferase:
a phosphatidyl-N-dimethylethanolamine + S-adenosyl-L-methionine→a phosphatidylcholine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.71)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information