MetaCyc Pathway: mixed acid fermentation in Paraburkholderia graminis OAS925

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Reactions and Genes RCH2_defined_glucose_5mM with Indole-3-pyruvic 1 mM
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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
ABIE53_001314 -3.9
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
ABIE53_003427 -1.6
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
ABIE53_000908 +0.3
ABIE53_005754 +0.0
ABIE53_006385 +0.0
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
ABIE53_004763 N.D.
ABIE53_005860 -0.4
ABIE53_005861 +0.0
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
No genes
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
ABIE53_003333 -0.1
ABIE53_004770 N.D.
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
ABIE53_001662 +0.2
ABIE53_003084 -3.8
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
ABIE53_006392 +0.1
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
ABIE53_001433 +0.2
ABIE53_005997 +0.3
ABIE53_006393 -0.2
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
ABIE53_004757 N.D.
ABIE53_004758 N.D.
ABIE53_005043 +0.5
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
ABIE53_001895 -0.7
ABIE53_003402 -0.1
ABIE53_004006 +0.1
ABIE53_004445 -0.0
ABIE53_005049 -0.5
ABIE53_005637 +0.1
ABIE53_005678 -0.2
ABIE53_006362 -0.1
ABIE53_006444 +0.2
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
ABIE53_004757 N.D.
ABIE53_004758 N.D.
ABIE53_005043 +0.5
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
ABIE53_003317 -0.3
ABIE53_004441 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information