MetaCyc Pathway: superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation in Bifidobacterium breve UCC2003

Add experiment(s):


Reactions and Genes Recovery broth with Streptomycin 0.3 mM
remove
N-acetyl-β-neuraminate→aceneuramate (EC 5.1.3.24)
No genes
N-acetylneuraminate lyase:
aceneuramate→N-acetyl-D-mannosamine + pyruvate
(EC 4.1.3.3)
No genes
N-acylmannosamine kinase:
N-acetyl-D-mannosamine + ATPN-acetyl-D-mannosamine 6-phosphate + ADP + H+
(EC 2.7.1.60)
BBR_RS11100 -0.1
BBR_RS16870 +1.0
BBR_RS18130 +1.4
N-acylglucosamine-6-phosphate 2-epimerase:
N-acetyl-D-mannosamine 6-phosphate→N-acetyl-D-glucosamine 6-phosphate
(EC 5.1.3.9)
BBR_RS11105 -0.1
N-acetylglucosamine-6-phosphate deacetylase:
N-acetyl-D-glucosamine 6-phosphate + H2O→D-glucosamine 6-phosphate + acetate
(EC 3.5.1.25)
BBR_RS11145 -0.5
BBR_RS14795 +0.3
BBR_RS16860 +0.1
Glucosamine-6-phosphate deaminase:
D-glucosamine 6-phosphate + H2O→β-D-fructofuranose 6-phosphate + ammonium
(EC 3.5.99.6)
BBR_RS11140 -0.1
BBR_RS14800 -0.0
BBR_RS16865 +0.1

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information