MetaCyc Pathway: CMP-N-acetylneuraminate biosynthesis II (bacteria) in Bacteroides thetaiotaomicron VPI-5482

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Reactions and Genes Varel_Bryant_medium_Glucose with Bile salts 0.5 mg/mL; pH 7
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UDP-N-acetyl-α-D-glucosamine + H2O→N-acetyl-α-D-mannosamine + H+ + UDP (EC 3.2.1.183)
BT0383 +1.6
BT0601 +0.1
BT1202 +0.1
BT1203 +0.1
BT2944 -0.4
N-acetylneuraminate synthase:
N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O→N-acetyl-β-neuraminate + phosphate (EC 2.5.1.56)
BT1714 +0.2
N-acylneuraminate cytidylyltransferase:
N-acetyl-β-neuraminate + CTP→CMP-N-acetyl-β-neuraminate + diphosphate (EC 2.7.7.43)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information