MetaCyc Pathway: L-phenylalanine degradation V in Pseudomonas stutzeri RCH2

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Reactions and Genes L-tyrosine (C)
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Phenylalanine 4-monooxygenase:
an N10-formyltetrahydrofolate + L-phenylalanine + dioxygen→4a-hydroxy-N10-formyltetrahydrofolate + L-tyrosine (EC 1.14.16.1)
Psest_0781 -2.5
4a-hydroxytetrahydrobiopterin dehydratase:
4a-hydroxy-N10-formyltetrahydrofolate→an N10-formyl-7,8-dihydrofolate + H2O (EC 4.2.1.96)
Psest_0780 N.D.
6,7-dihydropteridine reductase (in reverse):
an N10-formyl-7,8-dihydrofolate + NADH + H+→an N10-formyltetrahydrofolate + NAD+ (EC 1.5.1.34)
Psest_3987 +0.4
Psest_0930 -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information