MetaCyc Pathway: L-tyrosine degradation I in Pantoea sp. MT58

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Reactions and Genes Ying_OrganicAcid7 rep A; time point 3
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
IAI47_00100 +0.2
IAI47_01085 +0.1
IAI47_01110 +0.1
IAI47_03280 +0.2
IAI47_03285 -0.2
IAI47_06185 -0.1
IAI47_06350 -0.0
IAI47_07085 -4.7
IAI47_09620 +0.0
IAI47_12765 -1.9
IAI47_16465 +0.1
IAI47_17835 N.D.
IAI47_18095 -0.0
IAI47_19280 +0.1
IAI47_19310 +0.2
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
IAI47_01175 -0.1
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
No genes
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
No genes
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information