MetaCyc Pathway: TCA cycle VII (acetate-producers) in Pantoea sp. MT58

Add experiment(s):


Reactions and Genes Ying_AminoAcid20 rep C; time point 3
remove
2-oxoglutarate synthase:
2-oxoglutarate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→succinyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.3)
No genes
succinyl-CoA + acetate→acetyl-CoA + succinate (EC 2.8.3.18)
No genes
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
IAI47_10335 -1.1
IAI47_20435 -0.1
(S)-malate[in] + an electron-transfer quinone→oxaloacetate[in] + an electron-transfer quinol (EC 1.1.5.4)
IAI47_01100 +0.1
IAI47_20405 +0.0
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
IAI47_13770 -3.7
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
IAI47_09250 -0.5
IAI47_15770 N.D.
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
IAI47_09250 -0.5
IAI47_15770 N.D.
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
IAI47_11900 N.D.

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information