MetaCyc Pathway: gallate degradation III (anaerobic) in Klebsiella michiganensis M5al

Reactions and Genes	2-Deoxy-D-ribonic lithium salt 10 mM (C)
Gallate decarboxylase: gallate + H+→pyrogallol + CO2 (EC 4.1.1.59)
No genes
Pyrogallol hydroxytransferase: pyrogallol + 1,2,3,5-tetrahydroxybenzene→phloroglucinol + 1,2,3,5-tetrahydroxybenzene (EC 1.97.1.2)
No genes
Phloroglucinol reductase (in reverse): phloroglucinol + NADPH + H+→dihydrophloroglucinol + NADP+ (EC 1.3.1.57)
No genes
dihydrophloroglucinol + H2O→3-hydroxy-5-oxohexanoate + H+
No genes
Acetate CoA-transferase (in reverse): 3-hydroxy-5-oxohexanoate + acetyl-CoA→acetate + 3-hydroxy-5-oxohexanoyl-CoA (EC 2.8.3.8)
BWI76_RS23700	-3.5
3-hydroxy-5-oxohexanoyl-CoA + coenzyme A→acetyl-CoA + (S)-3-hydroxybutanoyl-CoA
No genes
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
BWI76_RS01365	-0.2
BWI76_RS01370	N.D.
BWI76_RS20455	+0.1
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase: acetate + butanoyl-CoA→acetyl-CoA + butanoate (EC 2.8.3.1; 2.8.3.8)
BWI76_RS23700	-3.5
Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
BWI76_RS03560	+0.6
BWI76_RS20240	N.D.
BWI76_RS20805	+0.6
BWI76_RS23150	-0.6
Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
BWI76_RS18090	-0.6
BWI76_RS20235	N.D.
BWI76_RS20815	-0.3
BWI76_RS20820	+0.2
BWI76_RS23200	-0.2

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information