MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Klebsiella michiganensis M5al

Reactions and Genes	2'-Deoxycytidine 10 mM (C)
Octopamine dehydratase: octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase: tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
BWI76_RS13080	-0.0
Monoamine oxidase: dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Synephrine dehydratase: (R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase: (4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
No genes
Aldehyde dehydrogenase (NAD(+)): 3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
BWI76_RS13085	-0.3
BWI76_RS21985	-1.8
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
BWI76_RS03825	+0.6
BWI76_RS03830	-0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information