MetaCyc Pathway: superpathway of pyrimidine ribonucleosides degradation in Klebsiella michiganensis M5al

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Reactions and Genes 2'-Deoxycytidine 10 mM (C)
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Cytidine deaminase:
cytidine + H+ + H2O→uridine + ammonium (EC 3.5.4.5)
BWI76_RS19610 -3.5
Pyrimidine-nucleoside phosphorylase:
uridine + phosphate→uracil + α-D-ribose-1-phosphate (EC 2.4.2.2; 2.4.2.3)
BWI76_RS01010 +0.2
BWI76_RS01295 +0.3
BWI76_RS04135 -5.7
BWI76_RS06200 +0.1
Dihydropyrimidine dehydrogenase (NADP(+)) (in reverse):
uracil + NADPH + H+→5,6-dihydrouracil + NADP+ (EC 1.3.1.2)
No genes
Dihydropyrimidinase:
5,6-dihydrouracil + H2O→3-ureidopropanoate + H+ (EC 3.5.2.2)
BWI76_RS17515 -0.2
Beta-ureidopropionase:
3-ureidopropanoate + 2 H+ + H2O→β-alanine + ammonium + CO2 (EC 3.5.1.6)
BWI76_RS07250 N.D.
BWI76_RS07550 +0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information