MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes malate (C) and Ammonium chloride (N); with TAPS
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Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium
(EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.4)
PFLU_RS14975 -0.1
PFLU_RS14985 -0.2
PFLU_RS19865 -0.0
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.4)
PFLU_RS14975 -0.1
PFLU_RS14985 -0.2
PFLU_RS19865 -0.0
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine
(EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+
(EC 1.2.1.53)
PFLU_RS16030 +0.3
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+
(EC 1.2.1.3)
PFLU_RS02715 +0.0
PFLU_RS04240 -0.2
PFLU_RS07400 +0.1
PFLU_RS09895 -0.2
PFLU_RS11535 +0.3
PFLU_RS15055 -0.1
PFLU_RS15075 +0.0
PFLU_RS15110 -0.2
PFLU_RS19825 -0.0
PFLU_RS20100 +0.2
PFLU_RS26745 -2.1
PFLU_RS29420 +0.4
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information