MetaCyc Pathway: fatty acid salvage in Klebsiella michiganensis M5al

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Reactions and Genes 2-Deoxy-D-ribonic lithium salt 10 mM (C)
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Butyrate--CoA ligase:
decanoate + ATP + coenzyme A→decanoyl-CoA + AMP + diphosphate
(EC 6.2.1.2; 6.2.1.3)
BWI76_RS17800 +0.1
decanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-dec-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
BWI76_RS02590 -0.1
Long-chain-enoyl-CoA hydratase (in reverse):
(2E)-dec-2-enoyl-CoA + H2O→(S)-3-hydroxydecanoyl-CoA
(EC 4.2.1.74)
BWI76_RS01365 -0.0
BWI76_RS01370 N.D.
BWI76_RS20455 +0.5
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxydecanoyl-CoA + NAD+→3-oxodecanoyl-CoA + NADH + H+
(EC 1.1.1.35)
BWI76_RS01365 -0.0
BWI76_RS01370 N.D.
BWI76_RS20455 +0.5
Acetyl-CoA C-acyltransferase (in reverse):
3-oxodecanoyl-CoA + coenzyme A→octanoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
BWI76_RS01360 +0.1
BWI76_RS13135 +0.6
BWI76_RS16135 +0.0
BWI76_RS20460 -0.2
BWI76_RS23445 -0.2
BWI76_RS23710 -3.8
octanoyl-CoA + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + CO2 + coenzyme A (EC 2.3.1.207)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information