MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Klebsiella michiganensis M5al

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Reactions and Genes 2-Deoxy-D-ribonic lithium salt 10 mM (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
No genes
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
No genes
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+ (EC 1.1.1.35)
BWI76_RS01365 -0.0
BWI76_RS01370 N.D.
BWI76_RS20455 +0.5
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
BWI76_RS01360 +0.1
BWI76_RS13135 +0.6
BWI76_RS16135 +0.0
BWI76_RS20460 -0.2
BWI76_RS23445 -0.2
BWI76_RS23710 -3.8
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+ (EC 3.1.2.23)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information