MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleoside salvage in Klebsiella michiganensis M5al

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Reactions and Genes 2'-Deoxycytidine 5 mM (C)
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Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5)
BWI76_RS19610 -3.5
Deoxycytidine kinase:
2'-deoxycytidine + a nucleoside triphosphate→dCMP + a nucleoside diphosphate + H+ (EC 2.7.1.74)
No genes
Deoxynucleoside kinase:
2'-deoxyuridine + ATP→dUMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
BWI76_RS17255 -0.3
(Deoxy)nucleoside-phosphate kinase:
dCMP + ATP→dCDP + ADP (EC 2.7.4.13; 2.7.4.14; 2.7.4.25)
BWI76_RS09775 N.D.
Thymidylate synthase:
dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45)
BWI76_RS14320 +0.1
Nucleoside-diphosphate kinase:
dCDP + ATP→dCTP + ADP (EC 2.7.4.6)
BWI76_RS06840 N.D.
BWI76_RS21100 -0.0
Deoxynucleoside kinase:
thymidine + ATP→dTMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
BWI76_RS17255 -0.3
T(2)-induced deoxynucleotide kinase:
dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9)
BWI76_RS11115 N.D.
Nucleoside-diphosphate kinase:
dTDP + ATP→dTTP + ADP (EC 2.7.4.6)
BWI76_RS06840 N.D.
BWI76_RS21100 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information