MetaCyc Pathway: superpathway of glycol metabolism and degradation in Klebsiella michiganensis M5al

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Reactions and Genes 2'-Deoxycytidine 5 mM (C)
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Lactaldehyde reductase:
ethylene glycol + NAD+→glycolaldehyde + NADH + H+ (EC 1.1.1.77)
BWI76_RS00645 -0.2
BWI76_RS22480 -0.0
Glycolaldehyde dehydrogenase:
glycolaldehyde + NAD+ + H2O→glycolate + NADH + 2 H+ (EC 1.2.1.21)
BWI76_RS13210 +0.4
BWI76_RS21985 -1.5
Glycolate dehydrogenase:
glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)
BWI76_RS17050 -0.5
Tartronate-semialdehyde synthase:
2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)
BWI76_RS06990 +0.1
Malate synthase:
glyoxylate + acetyl-CoA + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)
BWI76_RS01660 -0.3
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
BWI76_RS07000 +0.0
BWI76_RS24825 -0.1
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
BWI76_RS07025 +0.5
BWI76_RS22820 +0.5
BWI76_RS24820 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information