MetaCyc Pathway: L-lysine degradation I in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes RCH2 defined with copper (II) chloride 0.03 mM
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
Pf6N2E2_3334 -0.4
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
No genes
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
Pf6N2E2_261 +0.3
Pf6N2E2_3126 -0.0
Pf6N2E2_3131 -0.0
5-aminovalerate transaminase:
2-oxoglutarate + 5-aminopentanoate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
Pf6N2E2_373 -0.5
Pf6N2E2_4013 -2.1
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
Pf6N2E2_368 +0.4
2-oxoglutarate + glutarate + dioxygen→(S)-2-hydroxyglutarate + CO2 + succinate (EC 1.14.11.64)
No genes
(S)-2-hydroxyglutarate + an electron-transfer quinone→2-oxoglutarate + an electron-transfer quinol (EC 1.1.5.13)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information