MetaCyc Pathway: fatty acid β-oxidation I (generic) in Burkholderia phytofirmans PsJN

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Reactions and Genes adipate (C)
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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
BPHYT_RS03225 -0.1
BPHYT_RS09560 -0.1
BPHYT_RS13545 -3.4
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
BPHYT_RS09560 -0.1
BPHYT_RS13545 -3.4
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
BPHYT_RS02345 +0.7
BPHYT_RS03225 -0.1
BPHYT_RS03235 +0.1
BPHYT_RS03825 N.D.
BPHYT_RS06755 N.D.
BPHYT_RS06760 +0.1
BPHYT_RS08375 N.D.
BPHYT_RS08630 -0.2
BPHYT_RS09560 -0.1
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13345 -0.0
BPHYT_RS13545 -3.4
BPHYT_RS14830 -0.3
BPHYT_RS17335 +0.3
BPHYT_RS17350 N.D.
BPHYT_RS20025 +0.2
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 +0.1
BPHYT_RS27895 +0.5
BPHYT_RS28015 -0.1
BPHYT_RS28020 N.D.
BPHYT_RS28620 +0.8
BPHYT_RS35465 +0.5
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
BPHYT_RS03225 -0.1
BPHYT_RS06760 +0.1
BPHYT_RS09560 -0.1
BPHYT_RS13545 -3.4
BPHYT_RS34155 +0.2
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
BPHYT_RS02230 -0.1
BPHYT_RS03230 +0.1
BPHYT_RS08275 -0.0
BPHYT_RS09150 +0.3
BPHYT_RS09180 -0.5
BPHYT_RS09565 +0.2
BPHYT_RS17345 +0.3
BPHYT_RS21955 +0.7
BPHYT_RS29385 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information