MetaCyc Pathway: ketolysis in Burkholderia phytofirmans PsJN

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Reactions and Genes Protocatechuic Acid (C)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+
(EC 1.1.1.30)
BPHYT_RS06890 -0.2
BPHYT_RS11930 -0.4
BPHYT_RS13690 +0.4
BPHYT_RS20955 -0.1
BPHYT_RS35475 N.D.
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate
(EC 2.8.3.5)
BPHYT_RS13670 N.D.
BPHYT_RS13675 +0.1
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA
(EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230 -0.1
BPHYT_RS03230 -0.0
BPHYT_RS08275 +0.1
BPHYT_RS09150 +0.2
BPHYT_RS09180 +0.1
BPHYT_RS09565 -0.3
BPHYT_RS17345 +0.4
BPHYT_RS21955 +0.0
BPHYT_RS29385 -5.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information