| Reactions and Genes | Azelaic (C) |
|---|
| remove |
| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA (EC 5.3.3.8) |
| BPHYT_RS03225 | -0.0 |
| BPHYT_RS09560 | -2.8 |
| BPHYT_RS13545 | -0.5 |
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 5.1.2.3) |
| BPHYT_RS09560 | -2.8 |
| BPHYT_RS13545 | -0.5 |
| a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| BPHYT_RS02345 | +0.1 |
| BPHYT_RS03225 | -0.0 |
| BPHYT_RS03235 | +0.3 |
| BPHYT_RS03825 | N.D. |
| BPHYT_RS06755 | N.D. |
| BPHYT_RS06760 | +0.5 |
| BPHYT_RS08375 | N.D. |
| BPHYT_RS08630 | -0.1 |
| BPHYT_RS09560 | -2.8 |
| BPHYT_RS10815 | N.D. |
| BPHYT_RS11780 | N.D. |
| BPHYT_RS13345 | -0.0 |
| BPHYT_RS13545 | -0.5 |
| BPHYT_RS14830 | -0.1 |
| BPHYT_RS17335 | +0.3 |
| BPHYT_RS17350 | N.D. |
| BPHYT_RS20025 | +0.4 |
| BPHYT_RS25360 | N.D. |
| BPHYT_RS25695 | N.D. |
| BPHYT_RS27105 | -0.0 |
| BPHYT_RS27895 | +0.1 |
| BPHYT_RS28015 | -0.2 |
| BPHYT_RS28020 | N.D. |
| BPHYT_RS28620 | +0.1 |
| BPHYT_RS35465 | +0.6 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| BPHYT_RS03225 | -0.0 |
| BPHYT_RS06760 | +0.5 |
| BPHYT_RS09560 | -2.8 |
| BPHYT_RS13545 | -0.5 |
| BPHYT_RS34155 | -0.6 |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| BPHYT_RS02230 | -0.1 |
| BPHYT_RS03230 | -0.3 |
| BPHYT_RS08275 | +0.1 |
| BPHYT_RS09150 | +0.0 |
| BPHYT_RS09180 | +0.2 |
| BPHYT_RS09565 | -3.7 |
| BPHYT_RS17345 | +0.2 |
| BPHYT_RS21955 | -0.3 |
| BPHYT_RS29385 | -0.4 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information