MetaCyc Pathway: mixed acid fermentation in Pantoea sp. MT58

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Reactions and Genes Ying_Others16 rep B; time point 2
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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
IAI47_00895 -0.4
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
IAI47_08485 +0.3
IAI47_10840 +0.4
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
IAI47_09495 -0.0
IAI47_13375 -1.0
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
IAI47_02520 -2.6
IAI47_06755 -1.5
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
IAI47_04830 +0.1
IAI47_12880 -0.0
IAI47_12885 -0.1
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
IAI47_09055 +0.0
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
IAI47_13770 -4.2
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
IAI47_10335 -0.1
IAI47_20435 -0.1
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
IAI47_06320 +0.1
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
IAI47_06325 -0.3
IAI47_08505 -0.2
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
IAI47_09250 -0.0
IAI47_15770 N.D.
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
IAI47_03540 -0.0
IAI47_06705 -0.1
IAI47_08620 -0.6
IAI47_09055 +0.0
IAI47_14090 -0.0
IAI47_15740 +0.1
IAI47_17820 +0.1
IAI47_19645 +0.0
IAI47_21245 -0.2
IAI47_21460 +0.0
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
IAI47_09250 -0.0
IAI47_15770 N.D.
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
IAI47_11900 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information