MetaCyc Pathway: superpathway of L-tyrosine biosynthesis in Enterobacter sp. TBS_079

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Reactions and Genes Putrescine (N)
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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
MPMX20_01381 +0.4
MPMX20_01920 +0.1
MPMX20_03469 -0.5
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
MPMX20_04278 -4.2
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
MPMX20_03650 N.D.
MPMX20_04162 -4.2
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
MPMX20_04189 -4.4
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
MPMX20_00978 +0.4
MPMX20_04279 -2.1
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
MPMX20_01567 -4.6
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
MPMX20_03264 -5.9
Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
MPMX20_01201 -0.0
MPMX20_03466 -3.3
MPMX20_03468 -4.8
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (EC 1.3.1.12)
MPMX20_03468 -4.8
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
MPMX20_00272 -0.2
MPMX20_00609 +0.0
MPMX20_00612 +0.1
MPMX20_01049 -0.1
MPMX20_01059 +0.1
MPMX20_01157 -0.0
MPMX20_01586 -0.9
MPMX20_02048 -0.1
MPMX20_02230 -0.1
MPMX20_02425 -0.2
MPMX20_03003 -5.1
MPMX20_03220 -1.0
MPMX20_04048 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information