MetaCyc Pathway: stearate biosynthesis II (bacteria and plants) in Phocaeicola vulgatus CL09T03C04

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Reactions and Genes Ammonium chloride (N); Varel_Bryant_medium_Glucose_noMET_DTT_NaS_B12_noNitrogen
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Beta-ketoacyl-acyl-carrier-protein synthase I:
a palmitoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.41)
HMPREF1058_RS10580 +0.3
HMPREF1058_RS10610 +0.3
HMPREF1058_RS10620 -0.5
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
HMPREF1058_RS02795 N.D.
HMPREF1058_RS03405 -0.8
HMPREF1058_RS09165 +0.1
HMPREF1058_RS10575 +0.1
HMPREF1058_RS10625 +0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctadecanoyl-[acp]→a (2E)-octadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
HMPREF1058_RS08050 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-octadec-2-enoyl-[acp] + NADH + H+→a stearoyl-[acp] + NAD+ (EC 1.3.1.9)
HMPREF1058_RS14465 +0.8
HMPREF1058_RS18000 -0.7
Oleoyl-[acyl-carrier-protein] hydrolase:
a stearoyl-[acp] + H2O→stearate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Long-chain-fatty-acid--CoA ligase:
stearate + ATP + coenzyme A→stearoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
HMPREF1058_RS06250 +0.2
HMPREF1058_RS07620 +2.2
HMPREF1058_RS12785 +0.5
HMPREF1058_RS17680 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information