MetaCyc Pathway: superpathway of glucose and xylose degradation in Phocaeicola vulgatus CL09T03C04

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Reactions and Genes Ammonium chloride (N); Varel_Bryant_medium_Glucose_DTT_NaS_noNitrogen
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Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+
(EC 1.1.1.49)
HMPREF1058_RS18030 +0.1
Xylose isomerase:
α-D-xylopyranose→α-D-xylulofuranose
(EC 5.3.1.5)
HMPREF1058_RS06650 +0.1
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+
(EC 3.1.1.31)
HMPREF1058_RS05475 +0.0
HMPREF1058_RS18035 -0.1
Xylulokinase:
D-xylulose + ATP→D-xylulose 5-phosphate + ADP + H+
(EC 2.7.1.17)
HMPREF1058_RS06655 -0.5
Phosphogluconate dehydrogenase (decarboxylating):
D-gluconate 6-phosphate + NADP+→D-ribulose 5-phosphate + CO2 + NADPH
(EC 1.1.1.44)
HMPREF1058_RS18025 -1.2
Ribose-5-phosphate isomerase (in reverse):
D-ribulose 5-phosphate→D-ribose 5-phosphate
(EC 5.3.1.6)
HMPREF1058_RS15620 N.D.
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate
(EC 5.1.3.1)
HMPREF1058_RS07710 N.D.
Transketolase (in reverse):
D-ribose 5-phosphate + D-xylulose 5-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
(EC 2.2.1.1)
HMPREF1058_RS02705 +0.0
HMPREF1058_RS02710 +0.1
HMPREF1058_RS15625 N.D.
Transaldolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate
(EC 2.2.1.2)
HMPREF1058_RS03840 +0.2
Transketolase:
D-erythrose 4-phosphate + D-xylulose 5-phosphate→β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate
(EC 2.2.1.1)
HMPREF1058_RS02705 +0.0
HMPREF1058_RS02710 +0.1
HMPREF1058_RS15625 N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+
(EC 1.2.1.12)
HMPREF1058_RS06050 N.D.
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP
(EC 2.7.2.3)
HMPREF1058_RS15030 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
HMPREF1058_RS05420 -0.0
HMPREF1058_RS12285 N.D.
HMPREF1058_RS13980 -0.2
HMPREF1058_RS14725 -5.0
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O
(EC 4.2.1.11)
HMPREF1058_RS17225 -1.5
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP
(EC 2.7.1.40)
HMPREF1058_RS09670 N.D.
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+
(EC 1.1.1.28)
HMPREF1058_RS16545 +0.3
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+
(EC 1.1.1.27)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information