MetaCyc Pathway: spermidine biosynthesis II in Klebsiella michiganensis M5al

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Reactions and Genes RCH2_defined_noCarbon with Supernatant; Trichoderma virens G41 grown in Fungal_growth_media_mCAFEs_v1, filtered and pH-adjusted 0.5x
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Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP
(EC 2.7.2.4)
BWI76_RS00790 +0.3
BWI76_RS01790 -1.6
BWI76_RS04245 -2.6
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate
(EC 1.2.1.11)
BWI76_RS12880 -0.2
BWI76_RS20385 +1.0
BWI76_RS26220 N.D.
L-aspartate 4-semialdehyde + putrescine + NADPH + H+→carboxyspermidine + NADP+ + H2O (EC 1.5.1.43)
No genes
carboxyspermidine + H+→spermidine + CO2 (EC 4.1.1.96)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information