MetaCyc Pathway: heme b biosynthesis II (oxygen-independent) in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes Nitrate reduction, replicate C
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Uroporphyrinogen decarboxylase:
uroporphyrinogen-III + 4 H+→coproporphyrinogen III + 4 CO2 (EC 4.1.1.37)
Pf1N1B4_1532 N.D.
coproporphyrinogen III + 2 S-adenosyl-L-methionine→protoporphyrinogen IX + 2 CO2 + 2 5'-deoxyadenosine + 2 L-methionine (EC 1.3.98.3)
Pf1N1B4_3868 -2.6
Pf1N1B4_5783 -1.0
Pf1N1B4_5784 N.D.
Pf1N1B4_5785 N.D.
protoporphyrinogen IX[in] + 3 a menaquinone→protoporphyrin IX[in] + 3 a menaquinol (EC 1.3.5.3)
No genes
protoporphyrin IX + Fe2+→protoheme + 2 H+ (EC 4.98.1.1)
Pf1N1B4_2932 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information