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    • Fitness data for Rv3537 in Mycobacterium tuberculosis H37Rv

    Probable dehydrogenase
    SEED: 3-oxosteroid 1-dehydrogenase (EC 1.3.99.4)

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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    group condition fitness t score  
    carbon source cholesterol 100uM (C) -1.9 -6.4 compare
    carbon source cholesterol 100uM (C) -1.5 -4.7 compare
    stress 7H9 with Geneticin G418 0.35 mM -0.7 -2.7 compare
    stress 7H9 with Menadione 0.005 mM -0.4 -1.6 compare
    stress 7H9 with Levofloxacin 0.3 ug/mL -0.4 -2.0 compare
    stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.4 -1.6 compare
    stress 7H9 with Dicloxacillin 0.0069 mM -0.3 -1.4 compare
    stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.3 -1.2 compare
    stress 7H9 with Ramoplanin 0.009 mM -0.3 -1.5 compare
    stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.3 +1.6 compare
    no stress control no stress control +0.3 +1.2 compare
    no stress control no stress control +0.3 +1.5 compare
    stress 7H9 with Clofazimine 0.072 ug/mL +0.4 +1.9 compare
    stress 7H9 with Clofazimine 0.072 ug/mL +0.4 +1.7 compare
    pH pH 4.5 +0.4 +1.3 compare
    stress 7H9 with Ethambutol 0.75 ug/mL +0.4 +1.7 compare
    stress 7H9 with Bedaquiline 0.15 ug/mL +0.4 +2.1 compare
    stress 7H9 with Cumene hydroperoxide 0.05 mM +0.4 +2.3 compare
    stress 7H9 with Erythromycin 0.016 mM +0.5 +1.2 compare
    stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.5 +2.5 compare