Fitness data for Rv3370c in Mycobacterium tuberculosis H37Rv

Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase)
SEED: DNA polymerase III alpha subunit (EC 2.7.7.7)
KEGG: error-prone DNA polymerase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with Hygromycin B 0.0095 mM -0.4 -2.1 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.4 -2.1 compare
stress 7H9 with Menadione 0.005 mM -0.4 -1.9 compare
pH pH 4.5 -0.4 -1.2 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.4 -1.7 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.4 -1.6 compare
stress 7H9 with Sisomicin 0.07 mM -0.3 -1.7 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -0.3 -1.7 compare
stress 7H9 with Streptomycin 0.178 ug/mL -0.3 -1.8 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.3 -1.4 compare
stress 7H9 with Rifampicin 0.014 ug/mL -0.3 -1.6 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.3 -1.5 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.3 -1.4 compare
stress 7H9 with hypochlorite 0.4 vol% +0.3 +1.4 compare
stress 7H9 with Dicloxacillin 0.0069 mM +0.3 +1.6 compare
carbon source propionate (C) +0.4 +2.2 compare
no stress control no stress control +0.4 +2.1 compare
stress 7H9 with Lomefloxacin 0.0035 mM +0.4 +1.7 compare
stress 7H9 with Lomefloxacin 0.0035 mM +0.5 +2.1 compare
stress 7H9 with Norfloxacin 0.125 mM +0.5 +1.9 compare