Fitness data for Rv3366 in Mycobacterium tuberculosis H37Rv

Probable tRNA/rRNA methylase SpoU (tRNA/rRNA methyltransferase)
SEED: tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207)
KEGG: RNA methyltransferase, TrmH family, group 2

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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group condition fitness t score  
no stress control no stress control -2.0 -3.4 compare
stress 7H9 with Clofazimine 0.072 ug/mL -1.5 -2.9 compare
stress 7H9 with Linezolid 0.44 ug/mL -1.3 -2.1 compare
nitrogen source L-Glutamic 10 mM (N) -1.2 -1.9 compare
carbon source butyrate 10 mM (C) -1.2 -2.4 compare
stress 7H9 with Clofazimine 0.45 ug/mL -1.2 -2.4 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -1.2 -1.8 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -1.1 -2.1 compare
stress 7H9 with Clofazimine 0.072 ug/mL -1.0 -2.1 compare
carbon source heptadecanoic 250 uM (C) -1.0 -2.3 compare
stress 7H9 with Clofazimine 0.45 ug/mL -0.9 -1.4 compare
nitrogen source L-Serine 10 mM (N) -0.8 -1.1 compare
stress 7H9 with Rifampicin 0.00045 ug/mL -0.7 -1.7 compare
no stress control no stress control +0.8 +0.9 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.8 +1.7 compare
no stress control no stress control +0.8 +2.1 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.1 +0.8 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +1.2 +1.5 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +1.3 +1.3 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.6 +1.2 compare