Fitness data for Rv3309c in Mycobacterium tuberculosis H37Rv

Probable uracil phosphoribosyltransferase Upp (UMP pyrophosphorylase) (uprtase) (UMP diphosphorylase)
SEED: Uracil phosphoribosyltransferase (EC 2.4.2.9)
KEGG: uracil phosphoribosyltransferase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.1)


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group condition fitness t score  
nitrogen source L-Alanine 10 mM (N) -1.9 -3.0 compare
stress 7H9 with Chlorpromazine 0.054 mM -1.7 -2.4 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.7 -1.7 compare
nitrogen source L-Glutamic 10 mM (N) -1.6 -2.6 compare
nitrogen source L-Asparagine 10 mM (N) -1.3 -3.6 compare
nitrogen source L-Aspartic Acid 10 mM (N) -1.3 -3.2 compare
stress 7H9 with Linezolid 0.44 ug/mL -1.3 -1.9 compare
stress 7H9 with Amikacin di2 ug/mL -1.2 -1.8 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -1.2 -1.2 compare
nitrogen source L-Asparagine 10 mM (N) -1.2 -1.3 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +1.1 +2.5 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +1.1 +1.9 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +1.1 +2.2 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +1.2 +2.5 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +1.3 +2.9 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.4 +2.9 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.6 +3.3 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +1.7 +2.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.7 +2.9 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.8 +3.3 compare